University of Maryland School of Medicine (UMSOM) researchers, along with their colleagues, engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested, according to a … Read more
Introduction The dismal state of snake antivenom production A primer on snake venom heterogeneity A primer on snake antivenom Do computationally designed antivenoms actually solve anything? An addendum: the NYT article over universal antivenoms (Note: In case you were at … Read more
EnglishEnglish (pdf)SwedishSwedish (pdf) 9 October 2024 The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2024 with one half to David BakerUniversity of Washington, Seattle, WA, USA “for computational protein design” and the other … Read more
A key protein called Reelin may help stave off Alzheimer’s disease, according to a growing body of research. GSO Images/The Image Bank/Getty Images GSO Images/The Image Bank/Getty Images A key protein that helps assemble the brain early in life also … Read more
In the largest study of its kind, scientists have shown how protein “biomarkers” predict dementia 15 years before diagnosis. The research, published today in Nature Aging, shows how profiles of proteins in the blood accurately predict dementia up to 15 … Read more
Amyotrophic lateral sclerosis (ALS) is a terrible disease. No controversy in saying that – there is no treatment available, and as a motor neuron syndrome its end result is an early death as movement, speaking, swallowing, and finally breathing are … Read more
While the vast majority of well-structured single protein chains can now be predicted to high accuracy due to the recent AlphaFold [1] model, the prediction of multi-chain protein complexes remains a challenge in many cases. In this work, we demonstrate … Read more
As many countries urge populations to stay at home, many of us are paying more attention to our diets and how the food we eat can support our health. To help sort out the fact from the fiction, BBC Future … Read more
I last wrote about Deepmind’s efforts to predict protein folding and structure here, with their AlphaFold software. AlphaFold really performed very strongly in the 2020 protein folding challenge, and that got a lot of attention. Well, they’ve recently published a … Read more
A protein found in robins’ eyes has all the hallmarks of a magnetoreceptor and could help birds navigate using the Earth’s magnetic fields, according to a study published today (June 23) in Nature. The research, an intensive in vitro analysis … Read more